Document Detail

An attempt to isolate and identify allergens in lanolin.
MedLine Citation:
PMID:  6705514     Owner:  NLM     Status:  MEDLINE    
One sensitizer, a sterol, has previously been reported to be present in lanolin. In this study, a related substance, a sterol, with a molecular weight of 424 has been isolated. A few sensitive subjects did not react to this substance. Lanolin probably contains several sensitizers. Sensitization to lanolin in guinea pigs seems previously to have failed. In this study, a methanol extract of a lanolin preparation containing large amounts of sterols sensitized guinea pigs.
S Fregert; I Dahlquist; L Trulsson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  10     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-05-16     Completed Date:  1984-05-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  16-9     Citation Subset:  IM    
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MeSH Terms
Allergens / isolation & purification*
Chemical Fractionation
Guinea Pigs
Lanolin / analysis*
Patch Tests
Sterols / isolation & purification*
Reg. No./Substance:
0/Allergens; 0/Sterols; 8006-54-0/Lanolin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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