Document Detail

The athlete, cocaine, and lactic acidosis: a hypothesis.
MedLine Citation:
PMID:  3321984     Owner:  NLM     Status:  MEDLINE    
The muscular makeup of the sprint-trained athlete may make him especially susceptible to severe lactic acidosis from cocaine-induced seizures. Because of a high percentage of glycolytic muscle fibers (compared to the muscle fiber type of the endurance-trained athlete), the lactic acidosis and heat generated from muscular activity is much greater in the sprint-trained athlete than in the endurance-trained athlete. The role of cocaine in producing seizures and increasing glycolysis, both of which produce lactic acidosis, is discussed. The hypothesis is presented that the elite athlete may be at greater risk of death than the general population from lactic acidosis produced as a result of cocaine-induced seizures.
R A Giammarco
Related Documents :
10589144 - The female athlete triad: disordered eating, amenorrhea, and osteoporosis.
16504414 - Atrial fibrillation in athletes: implicit literature-based connections suggest that ove...
2344864 - Circulating met-enkephalin in trained athletes during rest, exhaustive treadmill exerci...
16822344 - Ginseng: is it in the root?
16891514 - Molecular analysis of fungal microbiota in samples from healthy human skin and psoriati...
15150354 - Exercise-induced acute renal failure associated with renal hypouricaemia: results of a ...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  294     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  1987 Dec 
Date Detail:
Created Date:  1988-01-28     Completed Date:  1988-01-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  412-4     Citation Subset:  AIM; IM    
Department of Medicine, State University of New York, Health Science Center, Syracuse 13210.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acidosis, Lactic / etiology*,  physiopathology
Doping in Sports*
Muscles / anatomy & histology,  physiology
Physical Education and Training
Seizures / complications
Reg. No./Substance:
Erratum In:
Am J Med Sci 1988 May;295(5):476

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Case report and review of the literature: ureteral endometriosis.
Next Document:  Atherosclerosis and its evolution in childhood.