Document Detail


An association of a variety of cardiovascular risk factors with low grade albuminuria in Korean men.
MedLine Citation:
PMID:  17134706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Recent studies have challenged the original definition of microalbuminuria when used to assess the risk of coronary heart disease or death. However, no large study has been conducted on Asian subjects regarding this topic to date. Therefore, we investigated the relationship between albuminuria below 17 microg/mg and other cardiovascular risk factors in apparently healthy Korean men. METHODS: We enrolled 2474 men with albuminuria below 17 microg/mg to participate in this study. We evaluated a variety of cardiovascular risk factors as well as the urine albumin creatinine ratio (UACR). The subjects were stratified into five groups by their UACR values and comparisons were made among the five groups. RESULTS: The comparisons showed that the UACR was progressively higher in subjects with a larger waist circumference and BMI as well as higher values for: serum triglyceride, glucose, hsCRP, and the systolic BP, in addition to a higher prevalence of diabetes and metabolic syndrome. When we excluded subjects with hypertension and diabetes, the results were similar. CONCLUSIONS: Our findings suggest that low grade albuminuria in Korean men was associated with a variety of cardiovascular risk factors, and this finding was unchanged when we excluded subjects with diabetes and hypertension. Further studies are warranted to evaluate the clinical implications of our findings.
Authors:
Ki Chul Sung; Byung Jin Kim; Seungho Ryu
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Publication Detail:
Type:  Journal Article     Date:  2006-11-28
Journal Detail:
Title:  Atherosclerosis     Volume:  196     ISSN:  1879-1484     ISO Abbreviation:  Atherosclerosis     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-14     Completed Date:  2008-02-29     Revised Date:  2010-03-29    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  320-6     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Pyung Dong, Jongro-Ku, Seoul, 110-746, Korea. kcmd.sung@samsung.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Albuminuria / complications*,  epidemiology,  ethnology
Biological Markers
Cardiovascular Diseases / epidemiology,  ethnology,  urine*
Cross-Sectional Studies
Diabetes Mellitus, Type 2 / epidemiology,  ethnology,  urine*
Humans
Hypertension / epidemiology,  ethnology,  urine*
Korea / epidemiology
Male
Metabolic Syndrome X / epidemiology,  ethnology,  urine*
Middle Aged
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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