Document Detail

The association of subclinical coronary atherosclerosis with abdominal and total obesity in asymptomatic men.
MedLine Citation:
PMID:  16034216     Owner:  NLM     Status:  MEDLINE    
The present study assesses and compares the association of waist circumference and body mass index with presence and severity of coronary artery calcium in asymptomatic men. The study population consisted of 451 asymptomatic men free of known coronary heart disease. The subjects were broadly divided into tertiles by waist circumference (< or =92 cm; 92.5-100 cm; > or =101 cm) and body mass index (< or =25.5 kg/m2; 25.6-28.4 kg/m2; > or =28.5 kg/m2), respectively. The risk of coronary artery calcium was two-fold higher among those with a waist circumference in the highest tertile (> or =101 cm) compared with men with waist circumference < or =92 cm. The relationship was found to be independent of body mass index, age, and conventional coronary heart disease risk factors. No significant association of body mass index with coronary artery calcium was observed. Our results are consistent with evidence that measures of central obesity, compared with body mass index, are more strongly related to clinical as well as subclinical coronary heart disease end points.
Khurram Nasir; Catherine Y Campbell; Raul D Santos; Ariel Roguin; Joel B Braunstein; Jose A M Carvalho; Roger S Blumenthal
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Preventive cardiology     Volume:  8     ISSN:  1520-037X     ISO Abbreviation:  Prev Cardiol     Publication Date:  2005  
Date Detail:
Created Date:  2005-07-21     Completed Date:  2005-09-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9813731     Medline TA:  Prev Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  143-8     Citation Subset:  IM    
The Ciccarone Preventive Cardiology Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
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MeSH Terms
Biological Markers / blood
Body Mass Index
Calcium / blood
Coronary Artery Disease / blood,  etiology*,  radiography
Cross-Sectional Studies
Lipids / blood
Middle Aged
Obesity / blood,  complications*
Retrospective Studies
Risk Factors
Severity of Illness Index
Tomography, X-Ray Computed
Reg. No./Substance:
0/Biological Markers; 0/Lipids; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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