Document Detail


An association study between polymorphisms in three genes of 14-3-3 (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein) family and paranoid schizophrenia in northern Chinese population.
MedLine Citation:
PMID:  15363479     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We performed an association study between three SNPs in the genes of 14-3-3 family and paranoid schizophrenia. SNP rs983583 G/A in the YWHAZ gene showed significant association with paranoid schizophrenia. Our study indicated that the YWHAZ gene was a potential susceptibility gene for paranoid schizophrenia in the population studied.
Authors:
Yanbin Jia; Xin Yu; Boyu Zhang; Yanbo Yuan; Qi Xu; Yucun Shen; Yan Shen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European psychiatry : the journal of the Association of European Psychiatrists     Volume:  19     ISSN:  0924-9338     ISO Abbreviation:  Eur. Psychiatry     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-14     Completed Date:  2005-01-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9111820     Medline TA:  Eur Psychiatry     Country:  France    
Other Details:
Languages:  eng     Pagination:  377-9     Citation Subset:  IM    
Affiliation:
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
China
DNA Primers / genetics
Enzyme Activation
Female
Gene Expression / genetics*
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
International Classification of Diseases
Male
Mixed Function Oxygenases / genetics*
Neuropsychological Tests
Polymerase Chain Reaction
Polymorphism, Genetic / genetics*
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide / genetics
Schizophrenia, Paranoid / diagnosis,  ethnology*,  genetics*
Tyrosine 3-Monooxygenase / genetics*
Chemical
Reg. No./Substance:
0/DNA Primers; EC 1.-/Mixed Function Oxygenases; EC 1.13.12.3/tryptophan 2-monooxygenase; EC 1.14.16.2/Tyrosine 3-Monooxygenase

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