Document Detail

The association of postural changes in systolic blood pressure and mortality in persons with hypertension: the Hypertension Detection and Follow-up Program experience.
MedLine Citation:
PMID:  3802437     Owner:  NLM     Status:  MEDLINE    
Participants in the Hypertension Detection and Follow-up Program (HDFP) were classified on the basis of baseline standing minus sitting systolic blood pressure into four groups (less than or equal to -20 [group 1], -19 to 0 [group 2], 1 to 20 [group 3], and greater than 20 mm Hg [group 4]) to study 5 year mortality. Group 1, 3.3% of the total, contained those participants who had postural hypotension. The 5 year total and age-adjusted mortality rates for these groups were significantly different (p less than .04), with group 1 having the highest rates. To account for the possible confounding effects of certain baseline risk factors--age, sex, race, prior antihypertensive treatment, randomization group, diabetes, end-organ damage, sitting diastolic and systolic blood pressures, pulse, hematocrit, smoking status, and relative weight (percent of ideal weight)--in assessing group differences in mortality rates, a multiple logistic model was used. Relative weight proved to be a confounding factor for the association of drop in postural systolic blood pressure with mortality. However, there is an interaction between history of diabetes and postural change in systolic blood pressure. Thus, postural hypotension may indicate a poor prognosis in diabetic hypertensive patients.
B R Davis; H G Langford; M D Blaufox; J D Curb; B F Polk; N B Shulman
Related Documents :
6861317 - Significance of systemic vascular resistance in determining the hemodynamic effects of ...
11334197 - Is compartment pressure related to plasma colloid osmotic pressure, in patients during ...
10709307 - Effects of non-invasive stimulation of acupoints on the cardiovascular system.
21913547 - Propofol versus halothane in paediatric daycase surgery: a comparison of the duration o...
1115127 - The effect of plasma retransfusion on the blood pressure in the puerperium.
14678347 - Acute systemic effects of inhaled salbutamol in asthmatic subjects expressing common ho...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  75     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-02-27     Completed Date:  1987-02-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  340-6     Citation Subset:  AIM; IM; S    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Actuarial Analysis
Blood Pressure
Diabetes Mellitus / mortality
Follow-Up Studies
Hypertension / mortality*
Hypotension, Orthostatic / mortality*
Mass Screening
Middle Aged
Models, Biological
Regression Analysis
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cardiovascular adaptations to intense swim training in sedentary middle-aged men and women.
Next Document:  Left ventricular geometry and function in adults with Ebstein's anomaly of the tricuspid valve.