| The association of macro- and microstructure of the corpus callosum and language lateralisation. | |
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MedLine Citation:
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PMID: 16157367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study aimed to examine how differences in functional lateralisation of language are related to interindividual variations in interhemispheric connectivity. Utilising an fMRI silent word-generation paradigm, 89 left- and right-handed subjects were subdivided into four lateralisation subgroups. Applying morphological and diffusion-tensor MRI, midsagittal cross-sectional area as well as quantitative measures of molecular diffusion (anisotropy, mean diffusion) of the corpus callosum were determined to assess interhemispheric connectivity. Statistical analyses revealed group differences in molecular diffusion but not in callosal size, which may be interpreted to reflect a stronger and/or faster interhemispheric connection in strongly left-lateralised subjects as compared to moderately left-lateralised, bilateral, or moderately right-lateralised subjects. |
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Authors:
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René Westerhausen; Frank Kreuder; Sarah Dos Santos Sequeira; Christof Walter; Wolfgang Woerner; Ralf Arne Wittling; Elisabeth Schweiger; Werner Wittling |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2005-09-12 |
Journal Detail:
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Title: Brain and language Volume: 97 ISSN: 0093-934X ISO Abbreviation: Brain Lang Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-03-14 Completed Date: 2006-05-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7506220 Medline TA: Brain Lang Country: United States |
Other Details:
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Languages: eng Pagination: 80-90 Citation Subset: IM |
Affiliation:
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Center for Neuropsychological Research, University of Trier, Germany. westerhausen@znf.uni-trier.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Corpus Callosum / anatomy & histology* Female Functional Laterality / physiology* Humans Language* Magnetic Resonance Imaging Male Verbal Behavior |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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