| The association of glomerular filtration rate and erectile dysfunction with severity of coronary artery disease in patients presenting with chest pain. | |
| | |
MedLine Citation:
|
PMID: 20039124 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: The most common cause of death in patients with chronic kidney disease is cardiovascular. Coexistence of reduced estimated glomerular filtration rate (eGFR) and erectile dysfunction (ED) may predate severe underlying coronary artery disease (CAD). The aim of this study was to evaluate the predictive value of presence and severity of ED and reduced estimated eGFR in the risk stratification of CAD in patients with chest pain. METHODS: Two hundred and sixty-five consecutive male patients with chest pain were included. All patients underwent exercise stress test (EST), of whom those with positive EST underwent coronary angiography. eGFR was calculated and sexual health inventory for men (SHIM) form was applied to evaluate ED. The relation between SHIM scores, eGFR and the number of arteries with significant lesions was evaluated. RESULTS: Of the 265 male patients, 105 had positive EST while the remaining 160 patients had negative EST. ED was present in 62 patients (38.8%) in the EST (-) group and in 64 patients (61%) in the EST (+) group (P = 0.000). In the EST (+) group, coronary angiography (CAG) revealed normal coronary anatomy or insignificant coronary lesions in 19 (18%), one-vessel disease in 45 (43%), two-vessel disease in 22 (21%) and three-vessel disease in 19 (18%) patients, respectively. The lowest ED prevalence (36.8%) was seen in patients who had normal coronary anatomy or insignificant coronary lesions while the highest prevalence was in those with three-vessel disease (89.5%). When eGFR were taken into account, there was a significant difference between the groups as well (107.2 ± 19.2 ml/min in the EST (-) group versus 94.1 ± 20.0 ml/min in the EST (+) group; P = 0.001). CONCLUSION: The presence and severity of ED and reduced eGFR are associated with the severity of underlying CAD in patients presenting with chest pain, and they could be implemented in the risk stratification of these patients. |
| | |
Authors:
|
Yalcin Solak; Hakan Akilli; Huseyin Atalay; Mehmet Kayrak; Hasan Gok; Suleyman Turk |
Related Documents
:
|
15202794 - Emergency department triage of patients with acute chest pain: definition of cardiac tr... 17599434 - Comparison of body mass index among patients with versus without angiographic coronary ... 12022524 - Cost-effectiveness of preoperative positron emission tomography in ischemic heart disease. 11481564 - Serial changes on quantitative myocardial perfusion spect in patients undergoing revasc... 10348244 - Relationships between several markers of extracellular matrix turn-over and ultrasonogr... 20480844 - Profile of signs and symptoms in mild and advanced acute appendicitis. |
Publication Detail:
|
Type: Journal Article Date: 2009-12-29 |
Journal Detail:
|
Title: International urology and nephrology Volume: 42 ISSN: 1573-2584 ISO Abbreviation: Int Urol Nephrol Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-11-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0262521 Medline TA: Int Urol Nephrol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 765-71 Citation Subset: IM |
Affiliation:
|
Meram School of Medicine, Nephrology Department, Selcuk University, 42090 Meram, Konya, Turkey. yalcinsolakmd@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Learning ethics through everyday problems: informed consent.
Next Document: Association between N-terminal pro-brain natriuretic peptide and acute ischemic stroke in patients o...