Document Detail


The association of fatty acid deficiency symptoms (FADS) with actual essential fatty acid status in cheek cells.
MedLine Citation:
PMID:  20356721     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Seven clinical symptoms have been utilised in several studies as a means of potentially identifying children with a deficiency in essential polyunsaturated fatty acids (PUFAs). The purpose of this study was to investigate whether there was any correlation between parental reports of the frequency of these seven 'fatty acid deficiency symptoms' (FADS) with actual levels of fatty acids in buccal cell samples of 450 children aged 8-10 years old. Additionally, the relationship between FADS and cognitive test performance, ratings of attention and behaviour and other somatic complaints were explored. The severity of reported FADS was not related to the levels of omega-6 or omega-3 in buccal cell samples. There was a relationship between parental reports of child behaviour and reported FADS; with high FADS being related to higher ratings of behaviour problems. Using FADS as a marker of PUFA deficiency may not be appropriate especially when assessing typically developing children.
Authors:
A Kirby; A Woodward; S Jackson; Y Wang; M A Crawford
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2010-03-31
Journal Detail:
Title:  Prostaglandins, leukotrienes, and essential fatty acids     Volume:  83     ISSN:  1532-2823     ISO Abbreviation:  Prostaglandins Leukot. Essent. Fatty Acids     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802730     Medline TA:  Prostaglandins Leukot Essent Fatty Acids     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  1-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
The Dyscovery Centre, Allt-yr-yn Campus, University of Wales, Newport NP20 5DA, UK.
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MeSH Terms
Descriptor/Qualifier:
Cells, Cultured
Cheek / pathology
Child
Fatty Acids, Essential / deficiency*,  metabolism*
Fatty Acids, Omega-3 / metabolism*
Fatty Acids, Omega-6 / metabolism*
Female
Humans
Lipid Metabolism Disorders / metabolism*,  pathology
Male
Syndrome
Chemical
Reg. No./Substance:
0/Fatty Acids, Essential; 0/Fatty Acids, Omega-3; 0/Fatty Acids, Omega-6

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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