Document Detail


The association of diabetes and dementia and possible implications for nondiabetic populations.
MedLine Citation:
PMID:  22014139     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Diabetes and prediabetic states have consistently been shown to be risk factors for cognitive decline, mild cognitive impairment and dementia. The importance of these findings is that diabetes and diabetes-related factors are modifiable, potentially permitting interventions aimed at postponing or preventing dementia. However, diabetes control cannot yet be implemented universally in diabetic subjects as a strategy for dementia prevention since the mechanisms by which diabetes impairs brain function and cognition are not fully understood. It is not clear which of the diabetes-related factors is crucial to this relationship. In addition, strict diabetic control has been demonstrated to carry risk for certain diabetic populations. The aim of the current article is to discuss current understanding of the relationships of diabetes and some of its characteristics with dementia, and suggest future questions to be answered.
Authors:
Ramit Ravona-Springer; Michal Schnaider-Beeri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of neurotherapeutics     Volume:  11     ISSN:  1744-8360     ISO Abbreviation:  Expert Rev Neurother     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101129944     Medline TA:  Expert Rev Neurother     Country:  England    
Other Details:
Languages:  eng     Pagination:  1609-17     Citation Subset:  IM    
Affiliation:
Sheba Medical Center, Tel Hashomer, Ramat Gan, 52621, Israel. ramit.ravona@sheba.health.gov.il.
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