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The association of chromium in household dust with urinary chromium in residences adjacent to chromate production waste sites.
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MedLine Citation:
PMID:  9831544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several previous studies of exposure to chromium waste in New Jersey have shown that Cr levels are elevated in household dust in homes adjacent to waste sites and that Cr levels in the urine of residents near sites are also elevated compared to control populations. It has not been possible until now, however, to examine these external and internal measures of exposure together in a large population to determine whether the external exposure is predictive of the internal exposure. We investigated the relationship between various adjusted and unadjusted measures of spot urine Cr concentration and household dust Cr from residents and residences adjacent to known Cr waste sites. Statistically significant bivariate relationships were found between log-transformed urine Cr concentration and Cr dust concentration (micrograms of Cr per gram of dust) but not Cr dust loading (nanogram Cr per square centimeter). Log-transformed urine concentration was used as the dependent variable in multiple regression analysis of the total population (n = 329), the population [less than/equal to] 10 years old (n = 67), and the population >10 years old (n = 262), with Cr dust concentration as a mandatory independent variable. Other potential direct influences on urine Cr were investigated as potential confounders of this relationship. In the final models for the entire population and those [less than/equal to] 10 years old, but not for those >10 years old, Cr dust concentration remained significant. This suggests that exposure of young children to Cr in household dust accounts for much of the relationship in the entire population.
Authors:
A H Stern; J A Fagliano; J E Savrin; N C Freeman; P J Lioy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Environmental health perspectives     Volume:  106     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-02-24     Completed Date:  1999-02-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  833-9     Citation Subset:  IM    
Affiliation:
Division of Science and Research, New Jersey Department of Environmental Protection, Trenton, NJ 08625 USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Air Pollution, Indoor / analysis*
Biological Markers / analysis
Child
Child, Preschool
Chromates*
Chromium / analysis*,  urine
Dust
Environmental Monitoring / methods*
Housing
Humans
Infant
Infant, Newborn
Middle Aged
New Jersey
Refuse Disposal*
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Chromates; 0/Dust; 7440-47-3/Chromium
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 12 Year: 1998
Volume: 106 Issue: 12
First Page: 833 Last Page: 839
ID: 1533240
PubMed Id: 9831544

The association of chromium in household dust with urinary chromium in residences adjacent to chromate production waste sites.
A H Stern
J A Fagliano
J E Savrin
N C Freeman
P J Lioy
Division of Science and Research, New Jersey Department of Environmental Protection, Trenton, NJ 08625 USA.



Article Categories:
  • Research Article


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