Document Detail

The association of cardiovascular disease and metabolic syndrome with nephrolithiasis.
MedLine Citation:
PMID:  22262248     Owner:  NLM     Status:  Publisher    
PURPOSE OF REVIEW: This review describes the relationship between nephrolithiasis, vascular disease and metabolic syndrome. RECENT FINDINGS: There is increasing evidence that kidney stone formation is associated with a number of systemic problems including cardiovascular disease, metabolic syndrome and its components. Some of these associations are bidirectional. The reasons for these associations are not totally clear, but potential factors include metabolic responses associated with these disorders that promote a stone forming milieu in urine, environmental factors such as diet, oxidative stress and inflammation and molecular changes impacting the transport of certain analytes in urine. SUMMARY: Urologists need to be cognizant of these associations as they may be able to contribute to an early diagnosis of a significant medical problem, or provide counseling to patients to prevent their occurrence.
Jessica N Lange; Patrick W Mufarrij; Kyle D Wood; Ross P Holmes; Dean G Assimos
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-18
Journal Detail:
Title:  Current opinion in urology     Volume:  -     ISSN:  1473-6586     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200621     Medline TA:  Curr Opin Urol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
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