| The association between interleukin-18 and pulmonary sarcoidosis: a meta-analysis. | |
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MedLine Citation:
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PMID: 20653400 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the association between interleukin-18 (IL-18) and pulmonary sarcoidosis. MATERIALS AND METHODS: The Medline, Embase and Cochrane databases were searched to identify relevant studies. Studies were eligible for inclusion if they enrolled newly-diagnosed, untreated pulmonary sarcoidosis patients with IL-18 measurement in bronchoalveolar lavage fluid (BALF) or blood. A randomized effects model was used to pool six relevant studies. RESULTS: The IL-18 levels of BALF and blood in patients with pulmonary sarcoidosis were significantly higher than those in control subjects (p = 0.0001, p = 0.04, respectively). CONCLUSION: This meta-analysis has observed some evidence showing that the published results from these studies indicated the statistically significant association between IL-18 and pulmonary sarcoidosis. |
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Authors:
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Ding-Hua Liu; Yun-Tai Yao; Wei Cui; Ke Chen |
Publication Detail:
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Type: Journal Article; Meta-Analysis |
Journal Detail:
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Title: Scandinavian journal of clinical and laboratory investigation Volume: 70 ISSN: 1502-7686 ISO Abbreviation: Scand. J. Clin. Lab. Invest. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-16 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404375 Medline TA: Scand J Clin Lab Invest Country: England |
Other Details:
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Languages: eng Pagination: 428-32 Citation Subset: IM |
Affiliation:
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Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. dinghua_liu@yahoo.cn |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Bronchoalveolar Lavage Fluid / chemistry Databases, Bibliographic Databases, Factual Female Humans Interleukin-18 / blood* Male Sarcoidosis, Pulmonary / blood*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Interleukin-18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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