Document Detail


An association between hypothyroidism and primary open-angle glaucoma.
MedLine Citation:
PMID:  8414419     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To test the hypothesis that there is an association between hypothyroidism and primary open-angle glaucoma. METHODS: The study was conducted in a case-control fashion. Sixty-four patients with primary open-angle glaucoma were evaluated for hypothyroidism by history and by undergoing a thyroid-stimulating hormone immunoradiometric assay. Sixty-four control subjects from the general eye clinic were evaluated in the same manner. Patients found to have elevated thyroid-stimulating hormone immunoradiometric assay were evaluated by an endocrinologist for hypothyroidism. RESULTS: Of the primary open-angle glaucoma group, 23.4% had hypothyroidism. A diagnosis was made previously in 12.5% patients, and 10.9% were newly diagnosed. Of the control subjects, 4.7% had hypothyroidism. A diagnosis had been made previously in 1.6% of the control subjects, and 3.1% were newly diagnosed. The difference between the two groups was found to be statistically significant. CONCLUSION: A statistically significant association between hypothyroidism and primary open-angle glaucoma is demonstrated. There is a large group (10.9%) of patients with primary open-angle glaucoma with undiagnosed hypothyroidism.
Authors:
K D Smith; B P Arthurs; N Saheb
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  100     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-11-08     Completed Date:  1993-11-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1580-4     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, McGill University, Montreal, Canada.
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MeSH Terms
Descriptor/Qualifier:
Aged
Case-Control Studies
Female
Glaucoma, Open-Angle / complications*,  diagnosis
Humans
Hypothyroidism / complications*,  diagnosis
Immunoradiometric Assay
Male
Thyroid Function Tests
Comments/Corrections
Comment In:
Ophthalmology. 1994 Apr;101(4):623-4   [PMID:  8152752 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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