| The association between food insecurity and mortality among HIV-infected individuals on HAART. | |
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MedLine Citation:
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PMID: 19675463 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Food insecurity is increasingly recognized as a barrier to optimal treatment outcomes, but there is little data on this issue. We assessed associations between food insecurity and mortality among HIV-infected antiretroviral therapy-treated individuals in Vancouver, British Columbia, and whether body max index (BMI) modified associations. METHODS: Individuals were recruited from the British Columbia HIV/AIDS drug treatment program in 1998 and 1999 and were followed until June 2007 for outcomes. Food insecurity was measured with the Radimer/Cornell questionnaire. Cox proportional hazard models were used to determine associations between food insecurity, BMI, and nonaccidental deaths when controlling for confounders. RESULTS: Among 1119 participants, 536 (48%) were categorized as food insecure and 160 (14%) were categorized as underweight (BMI < 18.5). After a median follow-up time of 8.2 years, 153 individuals (14%) had died from nonaccidental deaths. After controlling for adherence, CD4 counts, and socioeconomic variables, people who were food insecure and underweight were nearly 2 times more likely to die (adjusted hazard ratio = 1.94, 95% confidence interval = 1.10 to 3.40) compared with people who were not food insecure or underweight. There was also a trend toward increased risk of mortality among people who were food insecure and not underweight (adjusted hazard ratio = 1.40, 95% confidence interval = 0.91 to 2.05). In contrast, people who were underweight but food secure were not more likely to die. CONCLUSIONS: Food insecurity is a risk factor for mortality among antiretroviral therapy-treated individuals in British Columbia, particularly among individuals who are underweight. Innovative approaches to address food insecurity should be incorporated into HIV treatment programs. |
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Authors:
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Sheri D Weiser; Kimberly A Fernandes; Eirikka K Brandson; Viviane D Lima; Aranka Anema; David R Bangsberg; Julio S Montaner; Robert S Hogg |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of acquired immune deficiency syndromes (1999) Volume: 52 ISSN: 1944-7884 ISO Abbreviation: J. Acquir. Immune Defic. Syndr. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-28 Completed Date: 2009-11-17 Revised Date: 2013-01-31 |
Medline Journal Info:
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Nlm Unique ID: 100892005 Medline TA: J Acquir Immune Defic Syndr Country: United States |
Other Details:
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Languages: eng Pagination: 342-9 Citation Subset: IM; X |
Affiliation:
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Department of Medicine, Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94143-1372, USA. sheri.weiser@ucsf.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antiretroviral Therapy, Highly Active* British Columbia / epidemiology Female Food Supply / statistics & numerical data* HIV Infections / drug therapy*, epidemiology, mortality* Health Surveys Humans Male Middle Aged Poverty* Risk Factors Thinness |
| Grant Support | |
ID/Acronym/Agency:
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MH 79713-01/MH/NIMH NIH HHS; R01 MH054907/MH/NIMH NIH HHS; //Canadian Institutes of Health Research |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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