| The association between birthweight 4000 g or greater and perinatal outcomes in patients with and without gestational diabetes mellitus. | |
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MedLine Citation:
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PMID: 19376489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of the study was to examine the association between birthweight of 4000 g or greater and perinatal outcomes in women with and without gestational diabetes mellitus (GDM). STUDY DESIGN: This was a retrospective cohort study of 36,241 singleton pregnancies stratified by the diagnosis of GDM, with presence or absence of birthweight of 4000 g or greater. Outcomes examined included neonatal hyperbilirubinemia, hypoglycemia, respiratory distress syndrome (RDS), shoulder dystocia, and Erb's palsy. chi(2) tests and multivariable logistic regression analyses were used to control for confounders. RESULTS: In women with GDM, neonates with a birthweight of 4000 g or greater, compared with those with a birthweight of less than 4000 g, had higher frequencies of hypoglycemia (5.3% vs 2.6%; P = .04), RDS (4.0% vs 1.5%; P = .03), shoulder dystocia (10.5% vs 1.6%; P < .001), and Erb's palsy (2.6% vs 0.2%; P < .001). Even without GDM, these outcomes occurred more frequently in infants with birthweight of 4000 g or greater. GDM increases the odds of adverse outcomes associated with birthweight of 4000 g or greater, particularly shoulder dystocia (adjusted odds ratios [aORs], 16.4 [GDM] vs 9.6 [non-GDM] and Erb's palsy (aORs, 41.9 [GDM] vs 6.7 [non-GDM]). CONCLUSION: Birthweight of 4000 g or greater is associated with a higher incidence of adverse perinatal outcomes such that neonatal providers should be alerted. |
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Authors:
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Tania F Esakoff; Yvonne W Cheng; Teresa N Sparks; Aaron B Caughey |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-04-18 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 200 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-01 Completed Date: 2009-07-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 672.e1-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, School of Medicine, San Francisco, CA, USA. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight* Cohort Studies Diabetes, Gestational* Female Fetal Macrosomia / epidemiology*, etiology* Humans Pregnancy Pregnancy Outcome Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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