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The association between ambient air quality and cardiac rate and rhythm in ambulatory subjects.
MedLine Citation:
PMID:  25226341     Owner:  NLM     Status:  Publisher    
BACKGROUND: Acute increases in ambient air pollution have been associated with increased hospitalization for cardiac diseases and stroke. Triggering of cardiac arrhythmia by changes in air quality could theoretically predispose individuals to cardiac arrest or heart failure, or stroke through precipitation of atrial fibrillation. We investigated the association between air quality and cardiac rate and rhythm characteristics measured by ambulatory cardiac monitoring.
METHODS AND RESULTS: Daily ambient 3-h maximum concentrations of ozone, nitrogen dioxide and fine particulate matter, and an index summarizing these pollutants called the Air Quality Health Index (AQHI) were compared to the results of 24-h ambulatory cardiac monitoring performed for clinical purposes in 8662 patients and analyzed at the University of Ottawa Heart Institute, Canada, between 2004 and 2009. An interquartile increase in the daily 3h- maximum AQHI was associated with a 0.9% (95% CI 0.3%, 1.5%) increase in the daily maximum heart rate and a 1.17% (95% CI 1.07%, 1.29%) increase in heart block frequency. An interquartile increase in NO2 was associated with an increase in the percentage of time in atrial fibrillation of 4.39% (-0.15, 9.15) among those ≤50years old, and 7.1% (0.24, 14.5) among males.
CONCLUSIONS: We found evidence that air pollution may affect cardiac rate and rhythm. This may be one mechanism partially explaining the increase in strokes and cardiac events observed on days of higher air pollution.
Sabit Cakmak; Lisa Kauri; Robin Shutt; Ling Liu; Martin S Green; Marie Mulholland; Dave Stieb; Robert Dales
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-13
Journal Detail:
Title:  Environment international     Volume:  73C     ISSN:  1873-6750     ISO Abbreviation:  Environ Int     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  365-371     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Ltd.
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