Document Detail


The assignment by linkage mapping of four genes from human chromosome 22 to bovine chromosome 5 and 17.
MedLine Citation:
PMID:  11736808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polymerase chain reaction oligonucleotides were designed to amplify bovine specific sequences for four genes that are located on human chromosome 22 (HSA22): crystallin beta A4 (CRY B A4), parvalbumin (PVALB), tissue inhibitor of metalloproteinase 3 (TIMP3) and matrix metalloproteinase 11 (MMP11). Single strand conformation analysis of these bovine gene fragments defined polymorphisms within a population of three large half-sib families of three F1 Charolais x Brahman sires and a composite herd comprising an equal proportion of Africander, Brahman, Hereford and Shorthorn breeds (CSIRO pedigree). The DNA marker genotypes were used to define linkage associations to other DNA markers already placed on the CSIRO linkage map. The genes TIMP3 and PVALB were assigned to BTA5 and CRYbetaA4 and MMP11 to BTA17.
Authors:
F Ariza; B Harrison; R D Drinkwater
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Animal genetics     Volume:  32     ISSN:  0268-9146     ISO Abbreviation:  Anim. Genet.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8605704     Medline TA:  Anim Genet     Country:  England    
Other Details:
Languages:  eng     Pagination:  371-4     Citation Subset:  IM    
Affiliation:
Molecular Animal Genetics Centre, CSIRO, University of Queensland, Brisbane, Australia. marizabo@visto.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Cattle / genetics*
Chromosome Mapping* / veterinary
Chromosomes, Human, Pair 22*
Crystallins / genetics
Humans
Matrix Metalloproteinase 11
Metalloendopeptidases / genetics
Parvalbumins / genetics
Polymerase Chain Reaction / veterinary
Synteny
Tissue Inhibitor of Metalloproteinase-3 / genetics
beta-Crystallin A Chain
Chemical
Reg. No./Substance:
0/CRYBA4 protein, human; 0/Crystallins; 0/Parvalbumins; 0/Tissue Inhibitor of Metalloproteinase-3; 0/beta-Crystallin A Chain; EC 3.4.24.-/Matrix Metalloproteinase 11; EC 3.4.24.-/Metalloendopeptidases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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