| An assessment of sinus quality of life and pulmonary function in children with cystic fibrosis. | |
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MedLine Citation:
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PMID: 17181094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Treatment of patents with cystic fibrosis (CF) is primarily directed at the lungs. However, there is a growing feeling that the status of the sinuses may have a profound influence on the status of the lungs in these patients. A number of investigators have demonstrated a relationship among coexisting rhinitis, sinusitis, other upper airway conditions, and lung disease. Several studies have shown that treatment and resolution of sinusitis results in an improvement in a number of pulmonary conditions. We hypothesize that pulmonary function test scores will be lower in patients with CF with more severe sinusitis. METHODS: Consecutive CF patients were asked to complete a sinus-specific quality-of-life instrument, the 16-item Sino-Nasal Outcome Test (SNOT-16), and these scores, were compared to FEV, scores. RESULTS: Univariate analysis revealed a significant correlation between SNOT-16 and FEV1 in patients under the age of 12. There was a trend toward significance in the older children and evaluation of the raw data shows that children with the highest FEV, had the lowest SNOT-16. CONCLUSION: This study indicates that the severity of sinus disease correlates with the severity of pulmonary disease in CF patients under the age of 12. We plan to use the SNOT-16 to assess sinus interventions on pulmonary status. |
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Authors:
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Ellen M Friedman; Michael Stewart |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of rhinology Volume: 20 ISSN: 1050-6586 ISO Abbreviation: Am J Rhinol Publication Date: 2006 Nov-Dec |
Date Detail:
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Created Date: 2006-12-21 Completed Date: 2007-02-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807268 Medline TA: Am J Rhinol Country: United States |
Other Details:
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Languages: eng Pagination: 568-72 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA. emfriedm@texaschildrenshospital.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Cystic Fibrosis / complications, physiopathology*, psychology* Female Forced Expiratory Volume / physiology* Humans Male Quality of Life* Severity of Illness Index Sinusitis / complications, physiopathology*, psychology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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