Document Detail

An assessment of sinus quality of life and pulmonary function in children with cystic fibrosis.
MedLine Citation:
PMID:  17181094     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Treatment of patents with cystic fibrosis (CF) is primarily directed at the lungs. However, there is a growing feeling that the status of the sinuses may have a profound influence on the status of the lungs in these patients. A number of investigators have demonstrated a relationship among coexisting rhinitis, sinusitis, other upper airway conditions, and lung disease. Several studies have shown that treatment and resolution of sinusitis results in an improvement in a number of pulmonary conditions. We hypothesize that pulmonary function test scores will be lower in patients with CF with more severe sinusitis. METHODS: Consecutive CF patients were asked to complete a sinus-specific quality-of-life instrument, the 16-item Sino-Nasal Outcome Test (SNOT-16), and these scores, were compared to FEV, scores. RESULTS: Univariate analysis revealed a significant correlation between SNOT-16 and FEV1 in patients under the age of 12. There was a trend toward significance in the older children and evaluation of the raw data shows that children with the highest FEV, had the lowest SNOT-16. CONCLUSION: This study indicates that the severity of sinus disease correlates with the severity of pulmonary disease in CF patients under the age of 12. We plan to use the SNOT-16 to assess sinus interventions on pulmonary status.
Ellen M Friedman; Michael Stewart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of rhinology     Volume:  20     ISSN:  1050-6586     ISO Abbreviation:  Am J Rhinol     Publication Date:    2006 Nov-Dec
Date Detail:
Created Date:  2006-12-21     Completed Date:  2007-02-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807268     Medline TA:  Am J Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  568-72     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Cystic Fibrosis / complications,  physiopathology*,  psychology*
Forced Expiratory Volume / physiology*
Quality of Life*
Severity of Illness Index
Sinusitis / complications,  physiopathology*,  psychology*

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