| The assessment of patients' health-related quality of life during tuberculosis treatment in Wuhan, China. | |
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MedLine Citation:
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PMID: 15455595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To validate the SF-36 questionnaire in a Chinese population and to assess the patients' health-related quality of life (HQoL) during tuberculosis (TB) treatment. DESIGN: The SF-36 (Chinese version) scores of 102 TB cases before treatment, after the initial phase and at the end of treatment were compared with those of 103 control subjects. RESULTS: The SF-36 scores were valid (internal consistency > 0.4) and reliable (Cronchbach's micro > 0.7). Before treatment, all except the role-emotional, social function and mental health scales of the TB patients were lower than those of the controls (P < 0.01); the patients' scores increased significantly during treatment (P < 0.01). In a stepwise regression model, age (P < 0.01, OR 0.95), white blood cell count (P < 0.01, OR 0.92) and number of symptoms (P < 0.05, OR 0.99) were associated with the total SF-36 score. At completion of treatment, sex (P < 0.01, OR 0.25) and haemoglobin (P < 0.05, OR 0.88) remained at the end of the model. CONCLUSION: The SF-36 scores of TB patients are low before treatment, indicating a decline in HQoL, with physical scales most affected. However, scores increase over the course of treatment. The Chinese version of SF-36 is a reliable tool for monitoring HQoL throughout TB treatment. |
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Authors:
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D Chamla |
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Publication Detail:
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Type: Journal Article; Validation Studies |
Journal Detail:
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Title: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Volume: 8 ISSN: 1027-3719 ISO Abbreviation: Int. J. Tuberc. Lung Dis. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-09-30 Completed Date: 2004-11-26 Revised Date: 2006-06-12 |
Medline Journal Info:
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Nlm Unique ID: 9706389 Medline TA: Int J Tuberc Lung Dis Country: France |
Other Details:
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Languages: eng Pagination: 1100-6 Citation Subset: IM |
Affiliation:
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Médecins du Monde, Chengdu Centers for Disease Control and Prevention, Chengdu City, China. dichamla@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antitubercular Agents / therapeutic use* China Female Health Status* Humans Male Psychometrics Quality of Life* Questionnaires* Treatment Outcome Tuberculosis, Pulmonary / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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