Document Detail


The assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve.
MedLine Citation:
PMID:  24887684     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSOLUTE: QT variability parameters appear to be the most practical and sensitive biomarkers of proarrhythmic liability in rabbit hearts with reduced repolarization reserve. Absolute QT variability parameters could serve as surrogates for TdP in drug-safety investigations in isolated rabbit hearts with attenuated repolarization reserve.
Authors:
Szabolcs Orosz; Annamária Sarusi; Norbert Csík; Julius Gy Papp; András Varró; Sándor Farkas; Tamás Forster; Attila S Farkas; András Farkas
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-30
Journal Detail:
Title:  Journal of cardiovascular pharmacology     Volume:  -     ISSN:  1533-4023     ISO Abbreviation:  J. Cardiovasc. Pharmacol.     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-6-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902492     Medline TA:  J Cardiovasc Pharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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