| An assessment of the distortion of arteries due to sectioning in endomyocardial biopsies. | |
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MedLine Citation:
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PMID: 9120733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Arteries are usually studied morphometrically after pressurized fixation and resin embedding. These procedures are impracticable when dealing with diagnostic biopsies. The accuracy of arterial morphometry is determined partly by the degree of tissue distortion during section preparation. The axial ratios of 7340 arteries were measured in 353 endomyocardial biopsies from 23 patients and then compared with those expected from mathematical modelling. An excess of elliptical arteries was found. The distribution of orientation of the long axes of these best fitted a simulated 10 per cent linear distortion in the direction of microtomy. In conclusion, these results suggest that although there is some tissue distortion during sectioning, useful data may be obtained from morphometry of arteries in routinely processed endomyocardial biopsies. |
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Authors:
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J J Boyle; J Jenkins; I C McKay; A R McPhaden; G B Lindop |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pathology Volume: 181 ISSN: 0022-3417 ISO Abbreviation: J. Pathol. Publication Date: 1997 Feb |
Date Detail:
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Created Date: 1997-04-21 Completed Date: 1997-04-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0204634 Medline TA: J Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 243-6 Citation Subset: IM |
Affiliation:
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University of Glasgow Department of Pathology, U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Coronary Vessels / pathology* Endocardium / anatomy & histology* Heart Transplantation / pathology* Humans Models, Cardiovascular Paraffin Embedding Postoperative Care* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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