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An ascorbic acid sensor based on protein-modified Au nanoclusters.
MedLine Citation:
PMID:  23108453     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A simple fluorescence sensor for sensitive turn-off detection of ascorbic acid (AA) was developed by using protein-modified Au nanoclusters in aqueous media. The sensing mechanism is originated from the oxidation state change of Au nanoclusters controlled by AA. Under optimal experimental conditions, a good linear relationship between the relative fluorescence quenching intensity and the concentration of AA can be obtained in the range of 1.5 to 10 μM, with a detection limit as low as 0.2 μM. The proposed method is simple, efficient and reliable for monitoring of AA in some biological samples.
Authors:
Xianxiang Wang; Peng Wu; Xiandeng Hou; Yi Lv
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-30
Journal Detail:
Title:  The Analyst     Volume:  -     ISSN:  1364-5528     ISO Abbreviation:  Analyst     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372652     Medline TA:  Analyst     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
College of Chemistry, Analytical & Testing Center, Sichuan University, Chengdu, Sichuan 610064, China. houxd@scu.edu.cn lvy@scu.edu.cn.
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