| An artificial molecular switch that mimics the visual pigment and completes its photocycle in picoseconds. | |
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MedLine Citation:
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PMID: 19004797 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Single molecules that act as light-energy transducers (e.g., converting the energy of a photon into atomic-level mechanical motion) are examples of minimal molecular devices. Here, we focus on a molecular switch designed by merging a conformationally locked diarylidene skeleton with a retinal-like Schiff base and capable of mimicking, in solution, different aspects of the transduction of the visual pigment Rhodopsin. Complementary ab initio multiconfigurational quantum chemistry-based computations and time-resolved spectroscopy are used to follow the light-induced isomerization of the switch in methanol. The results show that, similar to rhodopsin, the isomerization occurs on a 0.3-ps time scale and is followed by <10-ps cooling and solvation. The entire (2-photon-powered) switch cycle was traced by following the evolution of its infrared spectrum. These measurements indicate that a full cycle can be completed within 20 ps. |
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Authors:
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Adalgisa Sinicropi; Elena Martin; Mikhail Ryazantsev; Jan Helbing; Julien Briand; Divya Sharma; Jérémie Léonard; Stefan Haacke; Andrea Cannizzo; Majed Chergui; Vinicio Zanirato; Stefania Fusi; Fabrizio Santoro; Riccardo Basosi; Nicolas Ferré; Massimo Olivucci |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-11-11 |
Journal Detail:
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Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 105 ISSN: 1091-6490 ISO Abbreviation: Proc. Natl. Acad. Sci. U.S.A. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2008-12-17 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7505876 Medline TA: Proc Natl Acad Sci U S A Country: United States |
Other Details:
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Languages: eng Pagination: 17642-7 Citation Subset: IM |
Affiliation:
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Dipartimento di Chimica, Università di Siena, via Aldo Moro 2, I-53100 Siena, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Isomerism Molecular Mimicry* Photochemistry Retinal Pigments / chemistry* Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Retinal Pigments |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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