Document Detail


An artificial molecular switch that mimics the visual pigment and completes its photocycle in picoseconds.
MedLine Citation:
PMID:  19004797     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Single molecules that act as light-energy transducers (e.g., converting the energy of a photon into atomic-level mechanical motion) are examples of minimal molecular devices. Here, we focus on a molecular switch designed by merging a conformationally locked diarylidene skeleton with a retinal-like Schiff base and capable of mimicking, in solution, different aspects of the transduction of the visual pigment Rhodopsin. Complementary ab initio multiconfigurational quantum chemistry-based computations and time-resolved spectroscopy are used to follow the light-induced isomerization of the switch in methanol. The results show that, similar to rhodopsin, the isomerization occurs on a 0.3-ps time scale and is followed by <10-ps cooling and solvation. The entire (2-photon-powered) switch cycle was traced by following the evolution of its infrared spectrum. These measurements indicate that a full cycle can be completed within 20 ps.
Authors:
Adalgisa Sinicropi; Elena Martin; Mikhail Ryazantsev; Jan Helbing; Julien Briand; Divya Sharma; Jérémie Léonard; Stefan Haacke; Andrea Cannizzo; Majed Chergui; Vinicio Zanirato; Stefania Fusi; Fabrizio Santoro; Riccardo Basosi; Nicolas Ferré; Massimo Olivucci
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-11
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  105     ISSN:  1091-6490     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-21     Completed Date:  2008-12-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  17642-7     Citation Subset:  IM    
Affiliation:
Dipartimento di Chimica, Università di Siena, via Aldo Moro 2, I-53100 Siena, Italy.
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MeSH Terms
Descriptor/Qualifier:
Isomerism
Molecular Mimicry*
Photochemistry
Retinal Pigments / chemistry*
Spectrophotometry, Ultraviolet
Spectroscopy, Fourier Transform Infrared
Time Factors
Chemical
Reg. No./Substance:
0/Retinal Pigments
Comments/Corrections

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