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An aromatic mystery.
MedLine Citation:
PMID:  22315643     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A case of antiepileptic hypersensitivity syndrome presenting as an acute septic illness is reported. A 67-year-old man, with a history of essential hypertension (treated with amlodipine) and recently diagnosed nocturnal epilepsy (treated with phenytoin), presented initially with an acute pneumonic illness with periorbital oedema. This was treated successfully with antibiotics and his phenytoin was changed to carbamazepine due to concerns regarding the periorbital oedema. He was re-admitted the following month with a history of weight loss, rigors, night sweats and high temperatures. Investigations revealed very high inflammatory markers. Despite extensive tests, no source of infection, autoimmune disease or malignancy was identified. The carbamazepine was then stopped and over the next 5 days the patient's symptoms gradually resolved. The patient's haematological and biochemical abnormalities returned to normal and he was discharged home. Since discharge he has been very well with no further sequelae.
Authors:
James Reid; Nick Balcombe; Kris Ghosh
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Publication Detail:
Type:  Journal Article     Date:  2010-02-08
Journal Detail:
Title:  BMJ case reports     Volume:  2010     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2010  
Date Detail:
Created Date:  2012-02-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Warwick Hospital, Geriatrics, Lakin Road, Warwick CV34 5BW, UK.
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