| An approach to the patient with retiform purpura. | |
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MedLine Citation:
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PMID: 21410606 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Retiform purpura consists of branching purpuric lesions caused by a complete blockage of blood flow in the dermal and subcutaneous vasculature. The differential diagnosis for retiform purpura is broad, including vasculitides of the small and medium vessels as well as microvascular occlusion due to thrombotic, infectious, and embolic phenomena. Determining the etiology of this important dermatologic sign can be a diagnostic challenge; however, an organized approach can improve the speed and accuracy of diagnosis and identify an effective treatment. This review focuses on early recognition, evaluation, and treatment of hospitalized patients with retiform purpura. Specifically, vasculitis, protein C and S deficiencies, heparin necrosis, warfarin necrosis, antiphospholipid antibody syndrome, disseminated intravascular coagulation, cryoglobulinemia, calciphylaxis, and cholesterol embolization syndrome will be discussed in detail. These conditions are commonly seen in consultative dermatology and can have multiorgan involvement, complicated laboratory evaluation, and long-term therapeutic implications. |
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Authors:
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Ashley Wysong; Priya Venkatesan |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Dermatologic therapy Volume: 24 ISSN: 1529-8019 ISO Abbreviation: Dermatol Ther Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-03-17 Completed Date: 2011-07-07 Revised Date: 2011-08-09 |
Medline Journal Info:
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Nlm Unique ID: 9700070 Medline TA: Dermatol Ther Country: Denmark |
Other Details:
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Languages: eng Pagination: 151-72 Citation Subset: IM |
Copyright Information:
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© 2011 Wiley Periodicals, Inc. |
Affiliation:
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Department of Dermatology, Stanford University, Stanford, CA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dermatology Diagnosis, Differential Early Diagnosis Hospitals* Humans Inpatients* Predictive Value of Tests Purpura / diagnosis*, etiology, therapy* Referral and Consultation Risk Factors Skin / pathology Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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