Document Detail


An approach to multi-copy search in molecular replacement.
MedLine Citation:
PMID:  11092928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The molecular-replacement method has been extended to a simultaneous search for multiple copies of the macromolecule in the unit cell. The central point of this approach is the construction of a multi-copy search model from the properly oriented monomers using a special translation function. The multi-copy search method has been implemented in the program MOLREP and successfully tested using experimental data.
Authors:
A Vagin; A Teplyakov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta crystallographica. Section D, Biological crystallography     Volume:  56     ISSN:  0907-4449     ISO Abbreviation:  Acta Crystallogr. D Biol. Crystallogr.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-01-04     Completed Date:  2001-01-25     Revised Date:  2007-07-24    
Medline Journal Info:
Nlm Unique ID:  9305878     Medline TA:  Acta Crystallogr D Biol Crystallogr     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  1622-4     Citation Subset:  IM    
Affiliation:
Department of Chemistry, University of York, Heslington, York YO1 5DD, England. alexei@ysbl.york.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Algorithms*
Calcium-Binding Proteins / chemistry
Crystallography / methods*
Crystallography, X-Ray
Humans
Immunoglobulin Fab Fragments / chemistry
Models, Theoretical
Nerve Growth Factors / chemistry
Protein Conformation
S100 Proteins*
Software*
Chemical
Reg. No./Substance:
0/Calcium-Binding Proteins; 0/Immunoglobulin Fab Fragments; 0/Nerve Growth Factors; 0/S-100 calcium-binding protein beta subunit; 0/S100 Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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