Document Detail

An appraisal of percutaneous treatment of liver metastases.
MedLine Citation:
PMID:  9649639     Owner:  NLM     Status:  MEDLINE    
Percutaneous treatments, such as ethanol injection and radiofrequency, have been recently proposed for the treatment of liver metastases. The aim of this study was to evaluate the effects of these treatments in a series of 8 patients who subsequently underwent liver resection. These patients had been treated with percutaneous methods between December 1995 and May 1997. In 6 patients, the primary tumor was colonic; in 2 patients, carcinoid; and in 1 patient, ileal leiomyosarcoma. The lesions were all initially small in size (1.5 to 3.5 cm), single in 7 patients, and multiple in 1 patient with a carcinoid tumor. The initial decision for percutaneous treatment had been made on subjective grounds by the radiologists who originally saw the patients. The number of percutaneous treatment sessions ranged from 2 to 21. In all patients, a progression of the disease occurred. Four patients underwent a right hepatectomy; 1 patient, a left lobectomy; 2 patients, a segmentectomy; and 1 patient, a wedge resection. There was no operative mortality in any of these 8 patients. Two patients presented with seeding of the neoplasm on the diaphragm, which was resected. Histologic examination of all surgical specimens revealed the presence of vital neoplastic tissue; only two specimens of carcinoid tumors showed more than 50% necrosis of the nodules treated percutaneously. These results led us to express doubts as to the efficacy of percutaneous ablative treatment for liver metastases.
A Mazziotti; G L Grazi; A Gardini; M Cescon; F Pierangeli; G Ercolani; E Jovine; A Cavallari
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society     Volume:  4     ISSN:  1074-3022     ISO Abbreviation:  Liver Transpl Surg     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-08-11     Completed Date:  1998-08-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9502504     Medline TA:  Liver Transpl Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  271-5     Citation Subset:  IM    
Copyright Information:
Copyright 1998 W.B. Saunders Company.
Policlinico S. Orsola, University of Bologna, Italy.
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MeSH Terms
Carcinoid Tumor / radiography,  secondary,  surgery*
Catheter Ablation
Colonic Neoplasms / pathology*,  radiography,  surgery
Ethanol / administration & dosage
Follow-Up Studies
Hepatectomy* / methods
Ileal Neoplasms / pathology*,  radiography,  surgery
Leiomyosarcoma / radiography,  secondary,  surgery*
Liver Neoplasms / radiography,  secondary,  surgery*
Middle Aged
Neoplasm Recurrence, Local
Retrospective Studies
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
Comment In:
Liver Transpl Surg. 1999 May;5(3):255-7   [PMID:  10375279 ]

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