Document Detail

An appraisal of the disc-macula distance to disc diameter ratio in the assessment of optic disc size.
MedLine Citation:
PMID:  10768018     Owner:  NLM     Status:  MEDLINE    
The disc-macula distance to disc diameter ratio (DM:DD ratio) has been advocated as a method of supporting the diagnosis of optic nerve hypoplasia. A DM:DD ratio of 3.00 has been claimed to be a satisfactory threshold value for this purpose. This study has critically evaluated the above claim and found a value of 3.00 to be too low. The threshold DM:DD ratio values for the diagnosis of unequivocal ONH for an adult population, 5 and 2 years of age were found to be respectively 4.20, 3.93 and 3.70, the values for the diagnosis of mild ONH being 3.68, 3.44 and 3.23. Lower computed values reduce the predictive power. The method of computation of the DM:DD ratio was modified to abolish potential error due to disc rotation and foveal displacement. In an adult population, there was no correlation between the DM:DD ratio and amblyopia or disc ovalness. There was a trend of increasing DM:DD ratio towards myopia and decreasing DM:DD ratio towards hypermetropia; the DM:DD ratio may therefore be falsely high in high myopia. DM:DD ratio values below threshold should therefore be interpreted with care until formal optic disc biometry can be performed.
D B Barr; C R Weir; A T Purdie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)     Volume:  19     ISSN:  0275-5408     ISO Abbreviation:  Ophthalmic Physiol Opt     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-04-24     Completed Date:  2000-04-24     Revised Date:  2006-11-07    
Medline Journal Info:
Nlm Unique ID:  8208839     Medline TA:  Ophthalmic Physiol Opt     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  365-75     Citation Subset:  IM    
Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK.
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MeSH Terms
Biometry / methods
Fluorescein Angiography*
Fovea Centralis / anatomy & histology
Middle Aged
Optic Disk / anatomy & histology*
Optic Nerve Diseases / diagnosis*
Reproducibility of Results

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