Document Detail


An apparatus for altering the mechanical load of the respiratory system.
MedLine Citation:
PMID:  3475270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe an apparatus for altering the mechanical load against which the respiratory muscles operate in humans. A closed system incorporates a rolling seal spirometer. The spirometer piston shaft is coupled to a fast-responding linear actuator that develops force in proportion to desired command signals. The command signal may be flow (resistive loading or unloading), volume (elastic loading or unloading), constant voltage (continuous positive or negative pressure), or any external function. Combinations of loads can be applied. Logic circuits permit application of the load at specific times during the respiratory cycle, and the magnitude of the loads is continuously adjustable. Maximum pressure output is +/- 20 cmH2O. The apparatus permits loading or unloading over a range of ventilation extending from resting levels to those observed during high levels of exercise (over 100 l/min). In response to a square-wave input, pressure rises exponentially with a time constant of 20 ms.
Authors:
M Younes; D Bilan; D Jung; H Kroker
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  62     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-08-28     Completed Date:  1987-08-28     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2491-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Respiration*
Ventilators, Mechanical*
Grant Support
ID/Acronym/Agency:
HL-32030/HL/NHLBI NIH HHS

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