Document Detail

The antitachycardia pacing ICD: impact on patient selection and outcome.
MedLine Citation:
PMID:  7681565     Owner:  NLM     Status:  MEDLINE    
Implantable cardioverter defibrillators (ICD) currently undergoing clinical investigation incorporate antitachycardia pacing capabilities, but little is known about their effect on patient selection and outcome. The Bilitch registry database was reviewed to compare the 1,553 patients who initially received standard devices with the 242 patients initially implanted with antitachycardia pacing ICDs (ANT). Baseline characteristics including mean age, ejection fraction, sex, type of cardiac disease, and percent presenting with sudden cardiac death were reviewed. Cumulative first shock occurrence and survival from arrhythmic and all cause mortality were calculated for the two groups. Results: Patient characteristics were similar in the two groups except that the ANT population had a greater male predominance and initially presented with a lower sudden cardiac death incidence (P < 0.05). Cumulative occurrence of first shock was significantly lower in the ANT group up to 24 months of follow-up (28% vs 36%, P < 0.05). ANT group survival from arrhythmic death (99% vs 96%) and all cause mortality (89% vs 94%) was significantly higher at 24 months of follow-up (P < 0.05). Conclusions: The addition of antitachycardia pacing to ICD therapy appears to significantly limit the occurrence of first ICD shock without adversely affecting mortality in a patient population similar to those implanted with standard ICDs.
J N Gross; R D Sackstein; S L Song; C J Chang; D T Kawinishi; S Furman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  16     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-27     Completed Date:  1993-04-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  165-9     Citation Subset:  IM    
Pacemaker Center, University of Southern California, Los Angeles.
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MeSH Terms
Death, Sudden, Cardiac / prevention & control*
Defibrillators, Implantable*
Equipment Design
Follow-Up Studies
Middle Aged
Pacemaker, Artificial*
Retrospective Studies
Survival Rate
Tachycardia, Ventricular / mortality,  therapy*
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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