Document Detail


The antihypertensive effect of peptides: a novel alternative to drugs?
MedLine Citation:
PMID:  18384915     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Many types of bioactive peptides that inhibit angiotensin I, angiotensin I converting enzyme (ACE) and Ang II type 1 receptor (AT1) in the cardiovascular system contribute to the prevention and treatment of hypertension. These inhibitory peptides are derived from many food proteins or artificial synthetic products. Further research examining the bioavailability of ACE inhibitory peptides will lead to the development of more effective ACE inhibitory peptides and foods. Our research also demonstrates that ACE inhibitory peptide LAP may lower blood pressure with no adverse effects.
Authors:
Fang Hong; Luo Ming; Sheng Yi; Li Zhanxia; Wu Yongquan; Liu Chi
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-02-16
Journal Detail:
Title:  Peptides     Volume:  29     ISSN:  0196-9781     ISO Abbreviation:  Peptides     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-12     Completed Date:  2008-08-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008690     Medline TA:  Peptides     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1062-71     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Tongji Hospital, Tongji University, Shanghai, China.
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MeSH Terms
Descriptor/Qualifier:
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Animals
Antihypertensive Agents / therapeutic use*
Humans
Hypertension / drug therapy
Peptide Fragments* / chemistry,  pharmacology,  therapeutic use
Pharmaceutical Preparations*
Receptors, Angiotensin / antagonists & inhibitors*
Renin-Angiotensin System / drug effects
Chemical
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents; 0/Peptide Fragments; 0/Pharmaceutical Preparations; 0/Receptors, Angiotensin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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