Document Detail


The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease.
MedLine Citation:
PMID:  21818123     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Regular exercise reduces the risk of chronic metabolic and cardiorespiratory diseases, in part because exercise exerts anti-inflammatory effects. However, these effects are also likely to be responsible for the suppressed immunity that makes elite athletes more susceptible to infections. The anti-inflammatory effects of regular exercise may be mediated via both a reduction in visceral fat mass (with a subsequent decreased release of adipokines) and the induction of an anti-inflammatory environment with each bout of exercise. In this Review, we focus on the known mechanisms by which exercise - both acute and chronic - exerts its anti-inflammatory effects, and we discuss the implications of these effects for the prevention and treatment of disease.
Authors:
Michael Gleeson; Nicolette C Bishop; David J Stensel; Martin R Lindley; Sarabjit S Mastana; Myra A Nimmo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-05
Journal Detail:
Title:  Nature reviews. Immunology     Volume:  -     ISSN:  1474-1741     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101124169     Medline TA:  Nat Rev Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Inflammation, Exercise and Metabolism Research Group, School of Sport, Exercise and Health Sciences, Loughborough University, Ashby Road, Loughborough, Leicestershire LE11 3TU, UK.
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