Document Detail

The ankle-brachial pressure index and a standardized questionnaire are easy and useful tools to detect peripheral arterial disease in non-claudicating patients at high risk.
MedLine Citation:
PMID:  17622205     Owner:  NLM     Status:  MEDLINE    
AIM: This observational study (Survey of Peripheral Arterial Disease Epidemiology, SPADE) evaluated the prevalence of asymptomatic peripheral arterial disease (PAD) in general practice. METHODS: PAD was determined as an ankle-brachial pressure index (ABI) <0.9 measured with Doppler ultrasound. Included patients had a history of ischemic events and/or risk factors for PAD, but no spontaneous complaints of intermittent claudication. Patients with an ABI <0.9 filled in a standardized questionnaire and their drug use was registered. A total of 4 536 patients was included. RESULTS: The prevalence of PAD was 18.7% for the total population, 26.5% for those with a history of ischemic events and 15.2% for those without such history. The prevalence increased with age, but was independent of gender. A standard questionnaire revealed leg pain when walking uphill or when hurrying in 2/3 of patients with an ABI <0.9 and in 45% criteria for claudication were met. CONCLUSION: ABI detects PAD in a considerable number of asymptomatic patients at increased risk and followed in general practice. When properly questioned almost half of these patients appear to have intermittent claudication.
M Sprynger; C Fassotte; R Verhaeghe
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  26     ISSN:  0392-9590     ISO Abbreviation:  Int Angiol     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-07-11     Completed Date:  2007-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
University Hospital Center of Liège, Liège, Belgium.
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MeSH Terms
Age Distribution
Belgium / epidemiology
Blood Pressure / physiology*
Brachial Artery / physiopathology*,  ultrasonography
Family Practice
Middle Aged
Peripheral Vascular Diseases / diagnosis,  epidemiology,  physiopathology*
Questionnaires / standards*
Risk Factors
Severity of Illness Index
Sex Distribution
Tibial Arteries / physiopathology*,  ultrasonography
Ultrasonography, Doppler, Duplex

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