| An animal model to study iron availability from human diets. | |
MedLine Citation:
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PMID: 405035 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The retention of ferric- and ferrous-iron was determined in guinea-pigs and monkeys using 55Fe and 59Fe. 2. The bioavailability of Fe from two typical Indian diets based on rice and wheat was determined in humans and monkeys using a 59Fe tracer and whole-body counting. 3. The retention ratio, ferric-Fe; ferrous-Fe was 0-90 in guinea-pigs and 0-33 in monkeys, indicating that monkeys absorb ferrous-Fe preferentially. 4. In monkeys retention of Fe from the test diets, as from ferrous ascorbate was lower than that in humans. 5. When food-Fe retention was expressed in relation to inorganic-Fe retention the value for retention ratio, food Fe: inorganic Fe in monkeys was similar to that in human subjects. 6. The results indicate that the monkey can be used as a model to study Fe absorption from human diets. |
Authors:
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B S Rao; J S Prasad; C V Sarathy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of nutrition Volume: 37 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 1977 May |
Date Detail:
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Created Date: 1977-07-29 Completed Date: 1977-07-29 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 451-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hypochromic
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etiology* Animals Biological Availability Cereals Diet* Disease Models, Animal* Guinea Pigs Haplorhini India Iron / metabolism* Iron Radioisotopes Macaca mulatta Whole-Body Counting |
| Chemical | |
Reg. No./Substance:
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0/Iron Radioisotopes; 7439-89-6/Iron |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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