| An angiographic evaluation of restenosis rate at a six-month follow-up of patients with ST-elevation myocardial infarction submitted to primary percutaneous coronary intervention. | |
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MedLine Citation:
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PMID: 18206252 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Percutaneous coronary intervention (PCI) is considered to be the optimal type of revascularization in patients with ST-segment elevation myocardial infarction (STEMI). However, the long-term effectiveness of this procedure can be reduced by restenosis. This investigation was aimed at a prospective evaluation, in a group of STEMI patients of "the real world" (not involved in randomised trials), of the angiographic restenosis rate at a 6-month follow-up, and at identifying the relationship between restenosis and the patients' characteristics. MATERIALS AND METHODS: Our study population consisted of 123 patients with STEMI submitted to primary PCI to then undergo stress echocardiography 3 months after PCI and an angiographic evaluation at a 6-month follow-up. RESULTS: a) In real life the restenosis rate is quite high (42.3%); b) no correlation was found between patients' clinical characteristics and restenosis; c) restenosis rate was higher in patients with bare metal stents than in those with drug-eluting stents (55.8% vs. 11.1%; p<0.001); in patients with longer stents (21.6+/-8.62 vs 18.1+/-6.34 mm, p=0.015) and when more than one stent was implanted. Moreover, a consistent number of patients showed restenosis though asymptomatic. CONCLUSIONS: Our data suggest that primary PCI is associated with a high incidence of angiographic restenosis. No correlation was found between patients' clinical characteristics and restenosis. The length and the number of implanted stents seem to be associated with a more probable restenosis at six-month angiographic evaluation. Drug-eluting stent implantation seems to be associated with a lower incidence of restenosis even in STEMI patients. |
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Authors:
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C Giglioli; S Valente; M Margheri; M Comeglio; M Chiostri; S M Romano; E Saletti; M Falai; T Chechi; G F Gensini |
Publication Detail:
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Type: Journal Article Date: 2008-01-18 |
Journal Detail:
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Title: International journal of cardiology Volume: 131 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-12 Completed Date: 2009-05-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 362-9 Citation Subset: IM |
Affiliation:
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Catheterisation Laboratory, Heart and Vessel Department, University of Florence, Florence, Italy. cristinagiglioli@yahoo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angioplasty, Transluminal, Percutaneous Coronary* Coronary Angiography* Coronary Restenosis / epidemiology, radiography* Drug-Eluting Stents Echocardiography, Stress Electrocardiography* Equipment Design Female Follow-Up Studies Humans Incidence Male Metals Middle Aged Myocardial Infarction / diagnosis, physiopathology*, therapy* Prospective Studies Stents Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Metals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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