Document Detail

The anesthetic and physiologic effects of an intravenous administration of a halothane lipid emulsion (5% vol/vol)
MedLine Citation:
PMID:  10072026     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: Halothane causes pulmonary dysfunction and death when given i.v. in liquid form. Six swine received a halothane lipid emulsion i.v. to evaluate the anesthetic and physiologic effects. No pulmonary toxicity or deaths were associated with the halothane lipid emulsion. The anesthetic profile was similar to delivery of halothane via a vaporizer.
J B Musser; J L Fontana; P D Mongan
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  88     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-03-25     Completed Date:  1999-03-25     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  671-5     Citation Subset:  AIM; IM    
Walter Reed Army Medical Center, Washington, District of Columbia, USA.
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MeSH Terms
Anesthetics, Inhalation / administration & dosage*,  blood,  toxicity
Carbon Dioxide / blood
Drug Carriers
Halothane / administration & dosage*,  blood,  toxicity
Hemodynamics / drug effects
Infusions, Intravenous
Lipids / administration & dosage*
Lung / drug effects
Lung Diseases / chemically induced
Oxygen / blood
Random Allocation
Reg. No./Substance:
0/Anesthetics, Inhalation; 0/Drug Carriers; 0/Emulsions; 0/Lipids; 124-38-9/Carbon Dioxide; 151-67-7/Halothane; 7782-44-7/Oxygen
Comment In:
Anesth Analg. 1999 Dec;89(6):1585   [PMID:  10589656 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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