Document Detail

The anemia of sarcoidosis.
MedLine Citation:
PMID:  3381019     Owner:  NLM     Status:  MEDLINE    
Anemia and leukopenia have been reported in sarcoidosis. In order to characterize the prevalence and association with disease activity, 75 patients with active pulmonary sarcoidosis were studied. One or more hematologic abnormalities were identified in 87% of patients studied. Anemia was present in 21 patients (28%), and bone marrow examination in 17 anemic patients revealed noncaseating granulomas in 9 patients and absent iron stores in 8 patients. The bone marrow aspirates did not show characteristics seen in other anemias of chronic disease, such as tuberculosis. In the majority of unexplained anemia cases, hemoglobin levels normalized with prednisone treatment. Forty-one of 75 patients (55%) had lymphopenia. Anemia found in patients with active sarcoidosis was associated with noncaseating granulomas in the bone marrow and an improvement with steroid therapy.
E E Lower; J T Smith; O J Martelo; R P Baughman
Related Documents :
8082339 - Radiographic findings in hiv-positive patients with sensitive and resistant tuberculosis.
11584179 - Extrapulmonary presentation of sarcoidosis.
15894779 - Subxiphoid pericardiostomy in the management of pericardial effusions: case series anal...
11243959 - Symptomatic persistent post-coronary artery bypass graft pleural effusions requiring op...
2956939 - Comparison of bronchoalveolar lavage helper/suppressor t-cell ratios in sarcoidosis ver...
25909 - Interpatient microbiological cross-contamination after dental radiographic examination.
20146069 - Slow saccades in bulbar-onset motor neurone disease.
12633899 - Neuroprotective effects of aspirin in patients with acute cerebral infarction.
9153449 - Steroid myopathy in cancer patients.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Sarcoidosis     Volume:  5     ISSN:  0393-1447     ISO Abbreviation:  Sarcoidosis     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-07-19     Completed Date:  1988-07-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8500778     Medline TA:  Sarcoidosis     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  51-5     Citation Subset:  IM    
Department of Internal Medicine, University of Cincinnati Medical Center, OH.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anemia / etiology*
Bone Marrow / pathology
Granuloma / pathology
Iron / blood
Leukopenia / etiology
Lung Diseases / blood,  complications*,  drug therapy
Prednisone / therapeutic use
Sarcoidosis / blood,  complications*,  drug therapy
Grant Support
Reg. No./Substance:
53-03-2/Prednisone; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Transbronchial lung biopsy in infiltrative lung disease. The importance of the pathologic approach.
Next Document:  Sarcoidosis autopsies in Japan. Frequency and trend in the last 28 years.