Document Detail


The anatomy, physiology and molecular pathways of vascular erectile dysfunction.
MedLine Citation:
PMID:  11329821     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vascular erectile dysfunction (VED) is composed of penile arterial insufficiency and veno-occlusive dysfunction. Both the arterial and venous dysfunctions are associated with cellular and molecular abnormalities. The goal of this work is to provide a summary of the gross anatomical and physiological abnormalities associated with VED and a theory of how these abnormalities result in VED based on the known molecular mechanism in cavernosal tissue and non-penile vascular tissue.
Authors:
M Vickers
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current medical research and opinion     Volume:  16 Suppl 1     ISSN:  0300-7995     ISO Abbreviation:  Curr Med Res Opin     Publication Date:  2000  
Date Detail:
Created Date:  2001-05-01     Completed Date:  2001-09-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0351014     Medline TA:  Curr Med Res Opin     Country:  England    
Other Details:
Languages:  eng     Pagination:  s37-41     Citation Subset:  IM    
Affiliation:
Surgical Service, Department of Veterans Affairs, Togus, Maine, USA. vickers@gwi.net
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MeSH Terms
Descriptor/Qualifier:
Angiotensin II / metabolism
Calcium Channels
Endothelin-1 / metabolism
Humans
Impotence, Vasculogenic / physiopathology*
Male
Muscle, Smooth, Vascular / metabolism
Nitric Oxide / metabolism
Potassium Channels
Chemical
Reg. No./Substance:
0/Calcium Channels; 0/Endothelin-1; 0/Potassium Channels; 10102-43-9/Nitric Oxide; 11128-99-7/Angiotensin II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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