| An analysis of peripheral blood burst forming units-erythroid in the polycythaemic states. | |
| | |
MedLine Citation:
|
PMID: 6622975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Peripheral blood burst forming units-erythroid (BFU-E) were measured by the plasma clot cell culture technique in patients with the various subtypes of polycythaemia and compared to normal. 10 patients with active polycythaemia rubra vera (PRV) were found to have a mean BFU-E level of 48 +/- 15.8 (SEM) per 5 X 10(5) cultured cells which was significantly different from normals (4 +/- 1.1, P less than 0.02), patients with controlled PRV (7 +/- 1.6, P less than 0.025), secondary polycythaemia (1 +/- 0.3, P less than 0.015) and relative polycythaemia (0, P less than 0.015). Burst forming units were found to fall to normal levels in patients with PRV with appropriate disease control and then to rise again in patients untreated for more than 18 months. Clinical aspects. Measurement of BFU-E levels from the peripheral blood could provide a useful adjunct from an accessible source in the differential diagnosis of polycythaemia as well as being of use in serial monitoring of patients with PRV. |
| | |
Authors:
|
E Yuen; J Gibson; K A Rickard; H Kronenberg |
Related Documents
:
|
19906625 - Rectal cell-associated hiv-1 rna: a new marker ready for the clinic. 19476435 - Interleukin 17 production among patients with american cutaneous leishmaniasis. 3127735 - Enhancement of lymphocytic sce frequencies in patients with ovarian cancer. 10465585 - Mutagen sensitivity in common cutaneous malignant melanoma and dysplastic naevus syndrome. 11289325 - Nasal polyposis: a study of its association with airborne allergen hypersensitivity. 11055825 - Significance of low mrna levels of interleukin-4 and -10 in mononuclear cells of the sy... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Scandinavian journal of haematology Volume: 31 ISSN: 0036-553X ISO Abbreviation: Scand J Haematol Publication Date: 1983 Oct |
Date Detail:
|
Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0404507 Medline TA: Scand J Haematol Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 293-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bloodletting Colony-Forming Units Assay* Erythrocytes / cytology Erythropoiesis* Erythropoietin / physiology Hematopoietic Stem Cells / cytology Humans Polycythemia / blood*, classification, therapy Polycythemia Vera / blood* |
| Chemical | |
Reg. No./Substance:
|
11096-26-7/Erythropoietin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Interstitial fluid pressure in human skin measured by micropuncture and wick-in-needle.
Next Document: Influence of human serum components on measurement of erythropoietin biological activity in vitro. S...