| An analysis of first authorizations for lipid-lowering drugs in Belgium. | |
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MedLine Citation:
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PMID: 12945474 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: In Belgium lipid-lowering drugs are reimbursed in primary and secondary prevention when after a non-specified diet of at least three months total cholesterol (TC) remains higher than 250 mg/dl or triglycerides (TG) remain higher than 200 mg/dl. Low-density lipoprotein cholesterol (LDL-C) is only taken into account for the reimbursement of fibrates when it remains higher than 160 mg/dl in secondary prevention. The aim of this study was to evaluate the changes in fasting lipoproteins levels among patients who wait for the reimbursement of a lipid-lowering drug. Additionally, the parameters influencing the physicians' choice to prescribe a statin or a fibrate were analysed. METHODS: In total 286 first authorizations for the reimbursement of lipid-lowering drugs were recorded during February and March of 2002 at two regional health insurance offices. We studied a mixed primary and secondary prevention population. RESULTS: The mean age at the initiation of the treatment was 61 years (SD = 12). Mean fasting TC was 285 mg/dl before the diet and 286 mg/dl after the diet. Fasting TC and TG did not decrease with the diet for respectively 51% and 54% of the patients. High TC and an improvement of TG during the diet were the only two factors correlated with the prescription of a statin instead of a fibrate. CONCLUSIONS: Half of the patients receiving lipid-lowering drugs in Belgium were not able to decrease their TC with diet before the initiation of the treatment. Cardiovascular risk factors were not taken into account for the reimbursement of statins. Belgian reimbursement criteria should be adapted. |
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Authors:
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D Devroey; W Betz |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Acta clinica Belgica Volume: 58 ISSN: 0001-5512 ISO Abbreviation: Acta Clin Belg Publication Date: 2003 May-Jun |
Date Detail:
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Created Date: 2003-08-29 Completed Date: 2003-09-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370306 Medline TA: Acta Clin Belg Country: Belgium |
Other Details:
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Languages: eng Pagination: 152-8 Citation Subset: IM |
Affiliation:
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Department of General Practice, University of Brussels, Laarbeeklaan 103, 1090 Brussels, Belgium. dirk.devroey@vub.ac.be |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antilipemic Agents / economics*, therapeutic use* Belgium Cohort Studies Dose-Response Relationship, Drug Drug Administration Schedule Drug Costs* Female Health Care Costs Humans Hypercholesterolemia / diagnosis, drug therapy*, economics Logistic Models Male Middle Aged Multivariate Analysis National Health Programs / economics* Prognosis Reimbursement Mechanisms / legislation & jurisprudence* Risk Assessment Socioeconomic Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents |
| Comments/Corrections | |
Comment On:
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Acta Clin Belg. 2003 May-Jun;58(3):149-51
[PMID:
12945473
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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