Document Detail


The amplitude ratio of the first to second heart sound is reduced in left ventricular systolic dysfunction.
MedLine Citation:
PMID:  19631396     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
In animal studies, the amplitude of the first heart sound (S1) is proportional to the rate of left ventricular pressure rise (LV dP/dt). To develop a clinical application for this property, we performed phono-electrocardiographic recordings using a digital hand-held device followed by an echocardiogram within 2 hours of a clinically indicated cardiac catheterization. Compared with the group with reduced dP/dt (<1000 mm Hg/s) or ejection fraction (EF) (<55%), the median S1/S2 detected at the cardiac base was higher in those with normal dP/dt or EF. On ROC analysis, S1/S2 significantly discriminated normal from reduced dP/dt and EF. This study demonstrated that S1, corrected for S2, is decreased in patients with impaired LV systolic function. Digital phonocardiography appears promising as an adjunctive bedside tool for evaluating left ventricular systolic function.
Authors:
Bill Pei Hsieh; Kamil Unver; Edward McNulty; Nelson B Schiller
Related Documents :
20549866 - Are dcd donors dead?
24826226 - Atrioventricular cross-talk leading to ventricular pacing inhibition in a dual-chamber ...
23979626 - Safety and efficacy of a totally subcutaneous implantable-cardioverter defibrillator.
6770386 - Reappraisal of some problems concerning the genesis of heart sounds.
11181466 - Healed plaque ruptures and sudden coronary death: evidence that subclinical rupture has...
21843256 - Ventricular torsion and untwisting: further insights into mechanics and timing interdep...
Publication Detail:
Type:  Letter; Research Support, Non-U.S. Gov't     Date:  2009-07-24
Journal Detail:
Title:  International journal of cardiology     Volume:  145     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  133-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Auditory evoked magnetic fields in children with functional hearing loss.
Next Document:  Main pulmonary artery aneurysm.