Document Detail

The Amplatzer vascular plug and Amplatzer vascular plug II for vascular occlusion procedures in 50 patients with congenital cardiovascular disease.
MedLine Citation:
PMID:  20552654     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To describe the use of the Amplatzer vascular plug (plug 1) and Amplatzer vascular plug II (plug 2) in patients with congenital cardiovascular disease (CCVD).
BACKGROUND: Plugs 1 and 2 have recently been made available. We report our experience describing plugs 1 and 2 in patients with CCVD highlighting the versatility of these devices.
METHODS: All patients with CCVD who underwent a vascular occlusion procedure at the Children's Hospital of Philadelphia between August 1, 2004 and July 30, 2009 with plug 1 or 2 were included. A retrospective review was performed.
RESULTS: Fifty patients underwent vascular occlusion procedure with plug 1 or 2 at a median age of 2.0 years (range 1 day to 47 years) and median weight of 12.3 kg (range 3.1-98 kg). Fifty-eight plugs (43% plug 1, 57% plug 2) were placed in 52 vessels. Of these vessels, 20 (38%) were patent ductus arteriosus (PDA), 14 (27%) venous collaterals, 5 (10%) aorto-pulmonary collaterals, 4 (8%) modified Blalock Taussig shunts, 3 (5%) porto-systemic connections, and 6 (12%) miscellaneous structures. Excluding a patient who was lost to follow-up, complete occlusion was observed in 100% of vessels either at the time of the catheterization or at follow-up. There were two complications (3.8%).
CONCLUSIONS: Plugs 1 and 2 are safe and effective devices that can be used in a variety of blood vessels in patients with CCVD. Plug 2 is particularly useful in closure of high-flow, tubular structures, especially type C PDA's.
Matthew Schwartz; Andrew C Glatz; Jonathan J Rome; Matthew J Gillespie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  76     ISSN:  1522-726X     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-14     Completed Date:  2011-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  411-7     Citation Subset:  IM    
The Children's Hospital of Philadelphia, Division of Cardiology, Philadelphia, PA, USA.
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MeSH Terms
Catheterization, Peripheral / adverse effects,  instrumentation*
Child, Preschool
Collateral Circulation
Ductus Arteriosus, Patent / therapy
Embolization, Therapeutic / adverse effects,  instrumentation*
Heart Catheterization / adverse effects,  instrumentation*
Heart Defects, Congenital / diagnosis,  physiopathology,  therapy*
Infant, Newborn
Middle Aged
Prosthesis Design
Retrospective Studies
Septal Occluder Device*
Treatment Outcome
Vascular Malformations / diagnosis,  physiopathology,  therapy*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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