| An alternative treatment option in tubal ectopic pregnancies with fetal heartbeat: aspiration of the embryo followed by single-dose methotrexate administration. | |
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MedLine Citation:
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PMID: 21601198 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To present 13 cases of unruptured tubal ectopic pregnancies successfully treated with ultrasound-guided aspiration and local and systemic methotrexate (MTX) administration. DESIGN: Case series. SETTING: University hospital. PATIENT(S): Thirteen women with an unruptured tubal ectopic pregnancy. INTERVENTION(S): Transvaginal ultrasound-guided aspiration of the tubal ectopic pregnancy followed by MTX administration into the gestational sac (half of the calculated total dose of 25 mg/m(2)) and intramuscular injection (the remaining half of the calculated total dose of 25 mg/m(2)). MAIN OUTCOME MEASURE(S): Recovery of the patients, successful conservative treatment of the tubal ectopic pregnancies with preservation of the fallopian tubes. RESULT(S): Twelve (92%) of 13 women were successfully aborted, without need for salpingectomy or salpingostomy. CONCLUSION(S): Transvaginal ultrasound-guided aspiration of fetus followed by local and systemic methotrexate administration can be safely used to treat unruptured tubal ectopic pregnancies. |
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Authors:
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Ismail Cepni; Onur Güralp; Pelin Ocal; Ramin Salahov; Hazel Gurleyen; Mehmet Idil |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2011-05-20 |
Journal Detail:
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Title: Fertility and sterility Volume: 96 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-07-04 Completed Date: 2011-08-29 Revised Date: 2012-01-10 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 79-83 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Obstetrics and Gynecology, Division of Reproductive Endocrinology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Drug Administration Schedule Female Heart Rate, Fetal* / physiology Humans Methotrexate / administration & dosage* Pregnancy Pregnancy, Ectopic / drug therapy, surgery, ultrasonography Pregnancy, Tubal / drug therapy*, surgery, ultrasonography* Retrospective Studies Suction / methods Treatment Outcome Ultrasonography, Interventional / methods Ultrasonography, Prenatal / methods Young Adult |
| Chemical | |
Reg. No./Substance:
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59-05-2/Methotrexate |
| Comments/Corrections | |
Comment In:
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Fertil Steril. 2011 Dec;96(6):e163; author reply e164
[PMID:
21982287
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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