| Alpha-lactalbumin-enriched and probiotic-supplemented infant formula in infants with colic: growth and gastrointestinal tolerance. | |
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MedLine Citation:
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PMID: 20517331 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies undertaken with alpha-lactalbumin-enriched formulae never addressed infants with colic. This study evaluated the nutritional adequacy, the gastrointestinal tolerance and the effect on colic of an alpha-lactalbumin-enriched and probiotic-supplemented formula. A double-blind, placebo-controlled study enrolled 66 healthy infants with colic, aged 3 weeks to 3 months, fed during 1 month with the either experimental formula (EF, Modilac Digest 1) or control formula (CF) and evaluated for efficacy and safety parameters at days 15 and 30. Weight and height gains were identical in the two groups and complied with standards (1023.4+/-360.4 g (EF) and 1047.4+/-372.1 g (CF), NS; 4.2+/-1.4 cm (EF) and 4.3+/-1.9 cm (CF), NS). No differences were found between groups for crying duration. 'Feeding-related' gastrointestinal side effects were significantly lower with EF than with CF (P=0.011). An alpha-lactalbumin-enriched and probiotic-supplemented formula guaranteed good weight and length gains to infants with colic and seemed to provide good gastrointestinal tolerance. |
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Authors:
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C Dupont; M Rivero; C Grillon; N Belaroussi; A Kalindjian; V Marin |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2010-06-02 |
Journal Detail:
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Title: European journal of clinical nutrition Volume: 64 ISSN: 1476-5640 ISO Abbreviation: Eur J Clin Nutr Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-07 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804070 Medline TA: Eur J Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 765-7 Citation Subset: IM |
Affiliation:
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Service de Néonatologie et Nutrition, Hôpital St Vincent de Paul, Université Paris Descartes, Paris, France. christophe.dupont@svp.aphp.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colic
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therapy* Dietary Supplements* Double-Blind Method Gastrointestinal Diseases / therapy* Growth / drug effects* Humans Incidence Infant Infant Formula* Lactalbumin / adverse effects, therapeutic use* Probiotics / therapeutic use* Prospective Studies |
| Chemical | |
Reg. No./Substance:
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9013-90-5/Lactalbumin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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