Document Detail

alpha-Fetoprotein levels in fullterm and very low birthweight infants.
MedLine Citation:
PMID:  2449887     Owner:  NLM     Status:  MEDLINE    
Plasma alpha-fetoprotein (alpha-FP) levels were determined in fullterm and very low birthweight (VLBW) infants in the first week of life and serially in a cohort of VLBW infants for the first 24 weeks after delivery. A rapid decline in alpha-FP levels was observed in both the fullterm and VLBW infants initially. Beyond 2 weeks of age, there was a gradual, linear decline until 6 weeks, followed by a more rapid period of decline from 6 to 16 weeks. The decline in the ensuing weeks demonstrated an asymptotic pattern. The half-life of alpha-FP was 7.5 days in the first week of life in both fullterm and preterm infants, 28.7 days from 2 to 6 weeks of life and 11.9 days from 6 to 16 weeks of life in VLBW infants.
K L Tan; A Loganath; A Mylvaganam; S M Karim; S R Kottegoda; S S Ratnam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Australian paediatric journal     Volume:  23     ISSN:  0004-993X     ISO Abbreviation:  Aust Paediatr J     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1988-03-25     Completed Date:  1988-03-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15420340R     Medline TA:  Aust Paediatr J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  285-7     Citation Subset:  IM    
University Department of Paediatrics, Kandang Kerbau Hospital, Singapore.
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MeSH Terms
Infant, Low Birth Weight / blood*
Infant, Newborn
Infant, Premature / blood
Reference Values
alpha-Fetoproteins / metabolism*
Reg. No./Substance:

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