Document Detail


The alcohol-deprivation effect in hybrid mice.
MedLine Citation:
PMID:  8508729     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hybrid mice (F1 CBA x C57Bl/6) after prolonged access to saccharin-menthol flavored 30% alcohol (FA) were deprived of it on two occasions, followed by test choices between (1) FA and water, and (2) FA and similarly flavored water. Although many mice failed to show deprivation-induced increases in FA intake, the mean rate of FA drinking during the first 1.5 h of renewed access was significantly increased even in the second test. Comparisons between the two tests suggest that flavor factors are generally less important than ethanol-seeking behavior.
Authors:
R M Salimov; N B Salimova
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Drug and alcohol dependence     Volume:  32     ISSN:  0376-8716     ISO Abbreviation:  Drug Alcohol Depend     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-07-12     Completed Date:  1993-07-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7513587     Medline TA:  Drug Alcohol Depend     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  187-91     Citation Subset:  IM    
Affiliation:
Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / genetics*
Animals
Ethanol / adverse effects
Hybridization, Genetic*
Male
Mental Recall
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Motivation*
Rats
Substance Withdrawal Syndrome / genetics
Taste / genetics*
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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