| The aging cardiovascular system: changes in autonomic function at rest and in response to exercise. | |
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MedLine Citation:
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PMID: 11915920 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tonic vagal modulation of cardiac period (R-R interval) decreases with advancing age, but is greater in middle-aged and older adults who habitually perform aerobic exercise compared with their sedentary peers. Cardiovagal baroreflex sensitivity also declines markedly with age in sedentary adults but only 50% as much in regularly exercising adults. In previously sedentary middle-aged and older adults, a 3-month program of moderate aerobic exercise increases cardiovagal baroreflex sensitivity by 25%. Tonic (basal) sympathetic nervous system (SNS) activity increases with advancing age in both sedentary and habitually exercising adults. Despite this, SNS beta-adrenergic support of energy metabolism (resting metabolic rate--RMR) declines with age in sedentary individuals. However, SNS beta-adrenergic support of RMR is maintained with age in endurance exercise-trained adults and therefore is much greater in middle-aged and older individuals who exercise regularly compared with their sedentary peers. Thus, regular aerobic (endurance) exercise modulates selective age-associated impairments in autonomic nervous system-physiological function. |
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Authors:
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D R Seals; K D Monahan; C Bell; H Tanaka; P P Jones |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: International journal of sport nutrition and exercise metabolism Volume: 11 Suppl ISSN: 1526-484X ISO Abbreviation: Int J Sport Nutr Exerc Metab Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2002-03-27 Completed Date: 2002-09-23 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100939812 Medline TA: Int J Sport Nutr Exerc Metab Country: United States |
Other Details:
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Languages: eng Pagination: S189-95 Citation Subset: IM |
Affiliation:
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Department of Kinesiology and Applied Physiology, University of Colorado, Boulder 80309, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging
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physiology* Autonomic Nervous System / physiology* Baroreflex / physiology Basal Metabolism Cardiovascular Physiological Phenomena* Exercise / physiology* Heart Rate / physiology Humans Physical Fitness / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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