Document Detail

The aetiology of prolapse.
MedLine Citation:
PMID:  18677434     Owner:  NLM     Status:  MEDLINE    
Female pelvic organ prolapse is a common condition that is said to be multifactorial in aetiology. While a number of risk factors such as vaginal childbirth, obesity and ageing are commonly accepted, it is not clear as to how these risk factors affect the development of prolapse-that is, which pathophysiologic mechanisms are responsible for disease manifestation. Measures used in epidemiological studies, such as presentation for surgical treatment, are generally confounded by other conditions, and evidence is lacking for some of the most frequently quoted aetiological factors. In this paper, I will try to summarise the available evidence in order to separate hearsay and hypothesis from available research findings and to suggest a way forward for diagnosis and treatment.
H P Dietz
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-08-02
Journal Detail:
Title:  International urogynecology journal and pelvic floor dysfunction     Volume:  19     ISSN:  -     ISO Abbreviation:  Int Urogynecol J Pelvic Floor Dysfunct     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-11     Completed Date:  2009-01-27     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  9514583     Medline TA:  Int Urogynecol J Pelvic Floor Dysfunct     Country:  England    
Other Details:
Languages:  eng     Pagination:  1323-9     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Nepean Clinical School, University of Sydney, Nepean Hospital, Penrith, New South Wales 2750, Australia.
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MeSH Terms
Genetic Predisposition to Disease
Hysterectomy / adverse effects
Obesity / complications
Risk Factors
Uterine Prolapse / etiology*

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