Document Detail


The aetiology of dental caries--an outline of current thought.
MedLine Citation:
PMID:  338498     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nearly 90 years after being put forward by W.D. Miller, the acidogenic theory of dental caries aetiology is supported by a wealth of experimental evidence. However, while explaining the basic mechanism of caries, it does not indicate how the effect of the mechanism is modified to give the observable pattern of caries attack. This explanation is attempted on the basis of the interaction of two groups of variable factors. Firstly, those which affect the tooth's resistance to caries attack, which include the chemical, microstructural and morphological nature of the enamel surface. Secondly the factors which determine the cariogenicity of the tooth's environment. These include the nature of the diet, plaque and saliva. Finally the caries initiation is considered at an atomic level in terms of the dynamic ionic exchange between enamel and plaque. This brief review highlights the need for considerably more research to shed more light on the nature of the variable aetiological factors of caries.
Authors:
R S Levine
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Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  International dental journal     Volume:  27     ISSN:  0020-6539     ISO Abbreviation:  Int Dent J     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-23     Completed Date:  1978-02-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374714     Medline TA:  Int Dent J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  341-8     Citation Subset:  D; IM; Q    
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MeSH Terms
Descriptor/Qualifier:
Bacteria / metabolism
Calcium / metabolism
Dental Caries / etiology*,  history,  microbiology
Dental Enamel / analysis,  metabolism,  ultrastructure
Dental Plaque / metabolism,  physiopathology
Diet
Dietary Carbohydrates / metabolism
Fluorides / metabolism
History, 19th Century
History, Ancient
Mouth / microbiology
Oral Hygiene
Osmolar Concentration
Phosphates / metabolism
Saliva / physiology
Tooth / anatomy & histology
Chemical
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Fluorides; 0/Phosphates; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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